Indicated in agricultural animals for prevention and treatment of: tetany ( tetany during pregnancy and lactation periods, transit  tetany, grass sickness, etc); postparturient paresis and paresis caused by calcium  or phosphorus deficiency; calcium/phosporus/magnesium exchange disorders (rickets, osteopathy, halisteresis, pregnancy, etc); oxonemia; lead/fluorine/oxalic acid poisoning (as an adjuvant therapy in combination with other treatment); toxicosis, allergy, bleeding diathesis, hematuria, hemoglobulinuria.

Impaired function of the parathyroid glands (spasmophilia, tetany), intensive calcium loss (particularly associated with long-lasting immobility), allergic diseases (angioneurotic edema, urticaria, hay fever, serum disease, etc.), including drug-induced; to reduce vascular wall permeability (radiation disease, hemorrhagic vasculitis); pleurisy, pneumonias, endometritis, adnexitis, skin diseases (psoriasis, eczema, pruritus); toxic liver damage, parenchymatous hepatitis, nephritis; eclampsia; paroxysmal myoplegia (hyperkalemic form). External and internal bleedings; as an antidote to poisoning with oxalic acid and its salts, with soluble salts of fluoric acid, and magnesium salts. It is used in combination with other drugs for induction of labor, for combined therapy (concurrently with anti-allergic agents) of allergies.

Diseases associated with hypocalcemia, increased cell membrane permeability, impaired transmission of nerve impulses in muscles. Hypoparathyroidism (latent tetany, osteoporosis), disturbances in vitamin D metabolism (rickets, spasmophilia, osteomalacia), hyperphosphatemia in patients with chronic renal failure. High calcium requirements (the period of intensive growth in children and adolescents, pregnancy, lactation), nutritional Ca2+ deficiency, disorders of calcium metabolism in postmenopausal period, bone fractures. Intensive loss of Ca2 + (long-term bedridden patients, chronic diarrhea, hypocalcemia, long-term administration of diuretics, antiepileptic drugs, corticosteroids). As a part of combined therapy of bleedings of varying genesis, allergic diseases (serum sickness, rash, fever syndrome, pruritus, itching dermatoses, angioneurotic edema); bronchial asthma, hunger edema, pulmonary tuberculosis, eclampsia, parenchymatous hepatitis, toxic liver damage, nephritis. Poisoning with magnesium salt, oxalic acid, soluble salts of fluoric acid (binding to calcium gluconate results in forming insoluble and non-toxic calcium oxalate and calcium fluoride).

Treatment for different forms of arterial hypertension, including ones resistant to other antihypertensive drugs.

Pulmonary tuberculosis (TB), caused by capreomycin sensitive mycobacterium in cases of inefficiency and intolerance of I-st line drugs.

Arterial hypertension. Heart failure. Captopril is indicated for the treatment of chronic heart failure with reduction of systolic ventricular function, it may be also used in combination with diuretics and, where appropriate, with digitalis drugs, beta-blockers. Myocardial infarction: for short-term (4 weeks) treatment of possible assignment of captopril for 24 hours after myocardial infarction in patients with stable condition; for prolonged prevention of symptoms of heart failure drug indicated for patients with clinically stable state with asymptomatic left ventricular dysfunction (ejection fraction ≤ 40%). Diabetic nephropathy in patients with diabetes mellitus I type, which is shown macroproteinuria.

Treatment of essential hypertension in adults. Treatment of adult patients with heart failure and impaired left ventricular systolic function (left ventricular ejection fraction ≤ 40 %) as adjunctive therapy inhibitors of angiotensin-converting enzyme (ACE) inhibitors or in cases of intolerance to ACE inhibitors.

Essential hypertension, where monotherapy with candesartan cilexetil or hydrochlorthiazide is insufficient.